Tongzhou Biotech New products in October

  1. Origin: Site      Author: Wren      Publish Time: 2023-10-02      

  2. 1、Etomidate (ETO) Rapid Test
  3. Etomidate is a anesthetic drug that is often used in combination with other anesthetic drugs during surgery. Since 2011, the misuse or abuse of etomidate has gradually increased when propofol was designated a controlled drug under the Narcotics Control Act in Korea. The major adverse effects of etomidate include adrenocortical suppression and unproven associated deaths, as well as myoclonus requiring pre-treatment. Although the issue of abuse and misuse of etomidate is emerging in recent years, there are few academic reports on these issues and analytical methods in the forensic field. In order to effectively manage the misuse or abuse of etomidate, it is necessary to continuously monitor related cases with great interest and to be more intensively studied on its abuse potential.
  4. Etomidate is one of the popular rapidly acting inducing agents with cardio-stable profile but associated with side effects such as myoclonus. Myoclonus can lead to regurgitation, prolapse of vitreous in open globe or many other complications.
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  7. 2、Mirtazapine (MTZ) Rapid Test
  8. Desmethylmirtazapine is a norepinephrine and specific serotonin antidepressant, which can act on central presynaptic α2 receptor antagonist and enhance adrenergic nerve conduction.
  9. The drug has been used clinically since 1990s as an antidepressants.  The effective dose for adults is usually 15-45 mg/d.  Adverse reactions include increased appetite, weight gain, sedationdizziness, somnolence, nausea, orthostatic hypotension and mania.  A single labeled oral Desmethylmirtazapine dose is eliminated in urine (85%) and feces (15%) over a one week period.
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  12. 3、N,N-Dimethyltryptamine (NND) Rapid Test
  13. N, N-Dimethyltryptamine is a powerful and illegal hallucinogenic drug. While there is an open debate on whether or not N, N-Dimethyltryptamine is addictive, this drug poses dangerous physical and psychological effects for frequent users. Additionally, individuals who frequently abuse N, N-Dimethyltryptamine often develop a dependence on the drug, proving the dangers of N, N-Dimethyltryptamine abuse.
  14. N, N-Dimethyltryptamine produces a high referred to as a psychedelic trip. When smoked, a N, N-Dimethyltryptamine trip usually begins instantly and lasts less than an hour. However, when drunk in the form of Ayahuasca tea, hallucinations begin after about 30 minutes and may last from 4-6 hours. Some users report experiencing mild, lingering hallucinogenic effects for several days after consuming or smoking N, N-Dimethyltryptamine. On a physiological level, N, N-Dimethyltryptamine causes an array of adverse side effects.
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  17. 4、Xylazine (XYL) Rapid Test
  18. Xylazine is a veterinary tranquilizer, which is not approved for human use in the United States, but is commonly used for sedating large animals. Although human intoxication with xylazine has been reported sporadically over the past several decades in a number of case studies. It was also noted in the literature describing drug overdose deaths in Philadelphia as early as 2006, yet it did not appear in high prevalence at that time. However, since the mid-2010 s, xylazine has been noticed by people who inject drugs (PWID) and public health practitioners as an increasingly commonplace additive in the street opioid supply of Philadelphia. Further, recent reports from connecticut implicated xylazine in a rising fraction of overdose deaths in 2019–2020.
  19. In Puerto Rico, heroin is commonly adulterated with xylazine. Also, xylazine is frequently found in speedball (a cocaine and heroin mixture). Xylazine has also been reported to be misused as a horse doping agent, a drug of abuse, a drug for attempted sexual assault, and as source of accidental or intended poisonings. From human reported cases, central nervous system depression, respiratory depression, bradycardia, hypotension, and hyperglycemia were observed.     Literature shows some similar pharmacologic effects between xylazine and heroin in humans.
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Post time: 2023-10-02 17:12:32
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